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Arthur Andrew Medical Neprinol AFD

Arthur Andrew Medical Neprinol is the strongest blend of systemic enzymes in the world.
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Neprinol is the strongest blend of systemic enzymes in the world.

Arthur Andrew Medical introduces a revolutionary blend of systemic enzymes including serrapeptase, nattokinase, protease, lipase, bromelain, papain, rutin and amla, as well as cofactors like coenzyme Q10 (CoQ10) and magnesium. Neprinol has been specially formulated to support healthy circulatory and immune function.* Systemic enzymes are similar to digestive enzymes, but primarily target the bloodstream rather than the gastrointestinal tract. These enzymes support healthy levels of Endogenous Blood Particles or EBPs.* EBPs can be pro-inflammatory proteins that normally accumulate in the blood.* Systemic enzymes essentially purify the blood of these EBPs, supporting healthy cardiovascular and liver function, as well as maintaining a healthy inflammatory response.* Neprinol's vegetarian enzyme blend tested to be more than 500% stronger in fibrinolytic activity than the leading animal based enzyme formulation, based on 3rd party fibrinolytic assay testing.†*Efficacy is of the utmost importance to doctor and patient alike, and Neprinol addressed this concern with a proven potency that can be utilized by healthcare professionals. Neprinol can be recommended for both clinical use and therapeutic applications.

Advanced Fibrin Defense

Fibrin is a protein formed in the human body. It is a major component of the normal scar tissue and blood clotting process. Healthy adults maintain normal fibrin equilibrium, where blood does not become too thick or thin.  Neprinol contains a blend of fibrinolytic (fibrin degrading) enzymes that can support healthy fibrin levels in the body.* When healthy, our bodies will normally secrete sufficient levels of plasmin, an enzyme which acts as a natural blood thinner.  Plasmin is responsible for maintaining normal blood solvency by removing unnecessary accumulated proteins specifically fibrin. Neprinol, like many fibrinolytic enzymes may support this normal fibrin removal process.*Nattokinase, an exceptional fibrinolytic enzyme, has been shown to support healthy fibrin levels. Neprinol also contains other enzymes, like bromelain and papain, that have been identified in animal and human studies to have properties that support normal blood viscosity.* Neprinol is an excellent choice for individuals that want to support healthy blood circulation.*

Frequently Asked Questions

What is Neprinol? 

Neprinol is a proprietary combination of Serrapeptase, Nattokinase, Protease, Lipase, Bromelain, Papain, Rutin, Amla and other proteolytic enzymes that are specially formulated to support healthy fibrin levels. Neprinol has been used to support immune and circulatory health, as well as maintain a healthy inflammatory response.* 

What are Enzymes? 

Enzymes are proteins (or protein-based molecules) that act as catalysts in biochemical reactions.  Every enzyme has a specific reactant known as a substrate, which can be thought of like a lock and a key.  Only a specific enzyme (or key) will react (or unlock) its substrate. This is the reason why enzymes are unable to break down necessary and vital tissue, as they only react with certain harmful proteins in the body. 

What are "Systemic Enzymes"? 

When enzymes are introduced into the bloodstream, they work "systemically", or throughout the entire body.  Taking enzymes on an empty stomach allows them to work systemically since they will bypass the upper digestive process and enter the bloodstream through the intestine.  Systemic enzymes are similar to digestive enzymes, though certain enzymes are better designed for systemic activity as opposed to digestion due to the materials they react with, such as Serrapeptase and Nattokinase.  These two enzymes are very efficient with the breakdown of a particular substance known as Fibrin. 

What is Fibrin? 

Fibrin is a protein substance naturally formed in the human body that plays a significant role in our health and general well-being.  Fibrin is responsible for scar tissue formation, and is produced as a reaction to injury.  Our bodies naturally maintain healthy fibrin levels with enzymes (principally plasmin) whose role is to attack and break down any excessive fibrin. As fibrin builds up in the body, it can cause many unhealthy conditions. 

Why Neprinol? 

As we age, our natural enzyme production decreases while the need for these enzymes is of increasing importance. Supplementing these valuable enzymes can combat enzyme deficiencies that can lead to a wide variety of health concerns.  Healthy levels of these enzymes can assist the body in maintaining a healthy immune system, healthy joints, proper circulation and an overall balanced reaction to injury. How 

Does Neprinol Work? 

By supplementing and replenishing the body's diminishing enzymes, Neprinol provides one of our most essential and basic biochemical needs.  It supplements the body's natural fibrinolytic enzyme levels thereby helping to maintain healthy fibrin levels: an underlying causative agent for many unhealthy conditions in the body 

Is Neprinol Enteric Coated? 

Enteric coatings are designed to protect enzymes and other supplements from stomach acid. Plastic-like chemicals known as phthalates are often used in this coating process. Phthalates are actually banned in children's toys in Europe and Mexico, so why would we ever include these in our formulas? Arthur Andrew Medical has instead developed an all-natural, chemical-free Acid Armor capsule. These capsules are comprised of an extra-thick layer of cellulose (vegetable capsules) with a micro threaded locking mechanism to prevent leaking. Acid Armor capsules have been designed to delay the release of the capsule's contents for up to an hour without the use of potentially harmful chemicals. 

Is Neprinol Safe? 

No serious or adverse side effects have been reported from taking systemic enzymes such as Neprinol*. If you are taking blood-thinning medication, you should consult with your physician before taking Neprinol.

Suggested use

When is the best time to take Neprinol? 

For best results, take the product at least one hour prior to eating and/or two hours after a meal. 

Can I take Neprinol with other supplements? 

Neprinol can be used safely with other dietary supplements. 

How long does it take for Neprinol to work? 

Although every person is different, some have reported feeling the effects of systemic enzymes in as little as 45 minutes. For therapeutic regimens, the progression may be slow for some and quicker for others. Typically, supplementing the product for a minimum of a month's time is recommended, with the best results occurring anywhere from one to three months thereafter.

Directions: Take 1 to 4 capsules with 8 oz of water between meals or as directed by your healthcare practitioner. For therapeutic applications, take 3 or 4 capsules three times daily.

Warning: Do not take Neprinol without the consent of your physician if you are taking anti-coagulants or if you are pregnant or nursing.

Supplement Facts

Serratiopeptidase (Serrapeptase)

A proteolytic (protein digesting) enzyme with potent fibrinolytic activity which may support healthy fibrin concentrations.* It has been clinically shown to thin secretions from the mucus membranes, and also promotes normal recovery after physical stress, boosting energy levels.*


A fibrinolytic enzyme that can help to maintain normal blood viscosity and normal cardiovascular health.* Like Serrapeptase, Nattokinase can support healthy fibrin concentrations.* It has antioxidant effects that may be beneficial to promote normal prostate health, and aids in the elimination of free radicals.*


Used systemically, this enzyme digests fats in the blood and can help to convert fats into fatty acids which may be expressed or retained as (energy).*


A proteolytic enzyme that, when present in blood serum, plays an important role in blood clotting as well as lysis of clots.* May be beneficial to help support a healthy immune system.*


Derived from Indian Gooseberry, Amla contains tannic acid, glucose, cellulose, and calcium. Amla helps maintain normal acid and pH balance, and has the highest concentration of any naturally derived vitamin C.*


A proteolytic enzyme derived from papaya that can promote normal healing of bruises and other tissue injuries.*


A proteolytic enzyme derived from pineapple that acts with the body to promote its normal immune responses.* Bromelain can also help in the maintenance or normal healthy skin.*


A flavonoid (plant pigment) that helps to maintain strong capillaries and connective tissue, as well as healthy blood vessels.*

Coenzyme Q10

Decreases the proliferation of free radicals, supporting a healthy immune system. *Co-Q10 helps promote maintenance of normal cardiovascular function and is a coenzyme that is essential for enzymes to function in the body.*


Promotes a healthy cardiovascular system, and is essential for cell repair, hormones and a regular heartbeat.* Magnesium helps reduce effects of increased stress.*

OTHER INGREDIENTS: Cellulose (Acid Armor™ capsules)
Neprinol is free of dairy, gluten and soy allergens.CONTAINS NO ARTIFICIAL COLORS OR PRESERVATIVES. 


Suggested Use
Directions: Take Neprinol with 8oz of water on an empty stomach. Larger amounts may be divided into 2 or 3 servings per day. Maintenance: 2-3 capsules per day. Increased Support: 6 capsules per day. Therapeutic: 9 capsules per day.
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